A Look At Topical Treatment Options For Acne
This article is an overview of the common topical agents used for treating acne: Benzoyl peroxide, retinoids, topical antibiotics, azelaic acid, and combination products.
Does Diet Really Affect Acne?
A review of studies, reviewing association between a high-glycemic-load diet, hormonal mediators, and acne risk.
The Noncompliant Patient with Acne
Patient adherence remains a serious challenge with acne patients. This article will review this problem and offer a number of suggestions, including dosing considerations and the use of laser/light devices, to better treat the non-adherent patient.
Acne Treatment: OTC (Non-Prescription)
This article is a brief overview of OTC (over the counter) treatment options for acne, which are available to patients without a prescription. Glycolic acid, salicylic acid, and benzoyl peroxide treatments are discussed, as well as other management of other factors like dry skin.
New Developments in Hormonal Therapy for Acne (Pharmacist Edition)
Oral contraceptives (OCs) have been used for many years by dermatologists as a treatment option for women with acne. The proven therapeutic benefits of OCs extend a valuable alternative to physicians for the treatment of acne.
Acne: Maximizing Effectiveness With Combination Therapy
Educate and counsel. Most patients with acne are teenagers who are very self-conscious about their looks and expect immediate treatment results. However, adult acne is becoming more common, and can be very distressing as well.
Adjunctive Skin Care for Acne (Pharmacist Edition)
Acne is among the most common dermatological disorders seen by dermatologists, affecting approximately 85% of people between the ages of 12 and 24 years. The use of adjunctive cleansers and moisturizers can help mitigate treatment side effects and subsequently enhance therapeutic efficacy.
The Use of Spironolactone To Treat Acne
Spironolactone is a diuretic and has anti-androgen effects, and can play a role in acne treatment. Its indications, potential side-effects, and contraindications are discussed.
Oral Antibiotics For Acne Treatment
Oral antibiotics are an important treatment option that is available for treating inflammatory acne. This portal provides an organized list of the most commonly used oral antibiotics for the treatment of acne.
1726 nm Lasers for the Treatment of Acne Vulgaris
Explore the efficacy of 1726 nm lasers, specifically AviClear and Accure systems, in treating moderate to severe acne vulgaris, offering a safe and effective alternative to systemic therapies.
Topical Acne Therapy: Current and Advanced Options for Optimizing Adherence
Topical treatment is the mainstay for mild acne, and adjunctive to oral or hormonal therapy for moderate acne. This article explores recent formulary advances and offers clinical strategies that can encourage adherence and improve treatment outcomes.
Laser Management of Acne Scarring
Acne scarring is often challenging to manage. This article discusses various laser treatments that are helpful in addressing abnormal color and texture in order to improve the appearance of an acne scar as well as review the appropriate use and side-effects of these treatments.
Understanding Truncal Acne: A Practical Guide to Diagnosis and Management
Truncal acne refers to AV affecting the chest and/or back, a common presentation in acne patients. This article offers guidance in clinical differentiation of truncal acne from other acneiform diseases and provides management recommendations.
The Use Of Low Dose Oral Contraceptives for the Management of Acne
There is compelling evidence that oral contraceptives (OCs) are effective in the management of mild-moderate acne vulgaris, as well as cumulative evidence that elevated levels of androgens in acne patients, relative to appropriate controls, are an underlying pathophysiological factor in acne.
Mild Acne: Treating & Diagnosing the First Pimple
Almost everyone at some point in his or her life will be troubled with mild acne. It can be related to athletic activities, travel, cosmetics, or hormonal changes. Various treatment options are discussed.
Natural Topical Retinoids with Emphasis on Tretinoin for the Treatment of Acne
Topical retinoids are the cornerstone of acne therapy and they can be used across the entire spectrum of acne severity. Selecting the most suitable retinoid formulation, as well as dispensing proper advice in terms of drug application, can improve patient compliance.
The Role of Skin Care in Optimizing Treatment of Acne and Rosacea
A triad approach to the treatment of acne and rosacea has been recommended. This integrated management approach includes patient education, selection of therapeutic agents, and initiation of an appropriate skin care regime. Appropriate skin care recommendations for patients with acne and rosacea will be discussed.
Topical Approaches in Combination Therapy for Acne (FP Edition)
Acne vulgaris is a chronic inflammatory cutaneous disease involving the pilosebaceous unit. This article discusses pathophysiology, sebum production, keratinization, and the role of P.acnes in acne formation.
Enhancing Bioavailability: Advances in Oral Isotretinoin Formulations
Discover advancements in oral isotretinoin formulations, including micronized isotretinoin, improving bioavailability and reducing food dependency for optimal acne treatment outcomes.
Adherence Optimization in Acne Management
Acne is a common dermatological condition found in about 85% of adolescents and young adults. Acne can have significant psychological, social or physical impacts. This article delves into the importance of patinet adherence and therapeutic strategies.
Isotretinoin (Accutane®) – Side Effects That Need Medical Monitoring By The Physician
Isotretinion will require monitoring by a doctor. While relatively rare, side-effects can be serious, and affect blood, bone, liver, neurologic, and muscle, and require periodic testing to ensure safety and healthy. It is also teratogenic, so pregnancy will also be a part in patient education.
A Review of Systemic Retinoid Therapy for Acne and Related Conditions
Oral isotretinoin, since its introduction more than 20 years ago, has been and still is the 'gold standard' in the treatment of acne and its variants. This is the only approach to acne with the possibility of a permanent “cure” or long term remission.
Management of Recalcitrant Acne
Acne treatment success involves a comprehensive approach that addresses diagnostic confounders, appropriate therapeutic options and patient adherence. Ongoing education and counselling will assist in meeting patient expectations and establishing a favourable rapport that promotes adherence.
Acne Surgical and Laser Treatment Options
Surgical and laser treatment options like microdermabrasion, photorejuvenation, scar revision laser treatments, and laser skin resurfacing are explored.
A Multimodal Approach to Acne-Induced Post-Inflammatory Hyperpigmentation: Trifarotene as a Long-Term Intervention
Discover how trifarotene, a fourth-generation retinoid, effectively treats acne and post-inflammatory hyperpigmentation (PIH). Learn about its benefits, clinical evidence, and role in managing acne sequelae.
Improving Bioavailability with a Novel Isotretinoin Formulation (Isotretinoin-Lidose)
Current practice guidelines recommend administration of oral isotretinoin with high-fat meals, which may pose issues with patient compliance. This article discusses Isotretinoin-Lidose (Epuris™), pharmacokinetics, bioavailability, and increased drug absorption rate, and how it may improve patient compliance.
A Physician’s Guide to Treating Acne
Acne is among the most common dermatological conditions seen in primary care. In this article, we provide a guide to address a growing need by primary care physicians to have a logical and practical approach to treating various forms of acne.
A Novel Fixed Dose Triple Combination Therapy (IDP-126) for Moderate to Severe Acne
IDP-126 is a novel fixed-dose topical gel combining clindamycin, benzoyl peroxide, and adapalene for moderate to severe acne. Approved by the FDA and Health Canada, it showed superior efficacy over dual therapies in phase 2 and 3 trials, with strong safety and tolerability outcomes.
New Developments in Hormonal Therapy for Acne
Oral contraceptives (OCs) are a valuable option for the treatment of women with acne. The use of OCs can be considered across the spectrum of acne disease severity in women. In Canada, three preparations are approved for mild-to-moderate acne, and a fourth is indicated for severe acne.
Topical Acne Treatment
Management of the patients’ expectations and compliance are crucial aspects of acne treatment. Disease chronicity and long-term treatment should be discussed at length during the initial consultation.
Topical Acne Therapy Advances in 2011
Acne vulgaris is a common disorder of the pilosebaceous follicle with multiple pathogenic factors. Topics like antibiotic treatment, antibiotic resistant, topical agents, are covered.
Polycystic Ovary Syndrome and Acne
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive aged women. This article will review the treatments for acne due to androgen excess in PCOS women.
Hormonal Agents Approved for Treatment of Acne
Hormonal agents are important, effective therapeutic options for women across the spectrum of acne severity. The three preparations approved in Canada for this indication have safety profiles similar to conventional oral contraceptives.
Advances in Understanding Atrophic Acne Scarring and the Role of Adapalene/Benzoyl Peroxide
There have been important advances in our understanding of acne scarring. Acne scars can resolve, and their evolution is determined by a balance between matrix repair and degradation. Timely, effective management of acne can minimize risk of subsequent acne scarring.
The Impact of Acne on Quality of Life
Optimal acne therapy must take into account not only acne type and severity, but also the impact of this skin disorder on the patient’s quality of life.
FDA Warning about Isotretinoin (Accutane., Roaccutane.)
On the 26th of February 1998, Hoffmann-LaRoche, on the instructions of the FDA, sent out more than 210,000 Dear Dr. warning letters to health care providers communicating new safety information about the prescribing of isotretinoin for acne, and citing isolated reports of drug-induced depression, psychosis and rarely, suicidal thoughts and action.
Minocycline as Acne Treatment Option
Minocycline is a tetracycline antibiotic which is used for acne treatment. This article provides an overview of minocycline, side-effects, brands, and drug interactions are discussed.
Optimizing Topical Acne Therapy
Acne vulgaris is a disease of the pilosebaceous follicle characterized by non-inflammatory (open and closed comedones) and inflammatory lesions. Its pathogenesis is multifactorial - the interplay of hormonal, bacterial, and immunological (inflammatory) factors results in the formation of acne lesions.
Topical Approaches in Combination Therapy for Acne (Pharmacist Edition)
This article delves into appropriate use of topical therapies for acne treatment. Appropriate agent selection, tolerance, adherence, follow-up, and considerations like complexity of treatment are discussed.
Acne Treatment: Other Types of Birth Control Pills
Progestin only and combination pills are discussed in this article. Monophasic, biphasic, and triphasic pills are considered and listed.